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After years in neurosurgery, here’s my take. Ozempic, Wegovy, and Mounjaro (GLP-1–based medications) are not cosmetic drugs. They target metabolic disease — and metabolic disease directly impacts the brain. What high-quality trials show: • SELECT (NEJM, 2023): Semaglutide reduced major cardiovascular events in overweight/obese adults without diabetes. • SUSTAIN-6 (NEJM, 2016): Semaglutide reduced stroke risk in patients with type 2 diabetes. • SURPASS program (2021–2023): Tirzepatide produced su
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TikTokall.in.one7553
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Glioblastoma is one of the most aggressive brain tumors known to medicine — and the biology behind why makes it especially devastating. 🧠 Neurons and mature muscle fibers don't typically divide, which is why they rarely form tumors. But glial cells do divide — and when they accumulate enough DNA mutations, that division can spiral out of control. The result is a glioblastoma, most commonly arising from astrocytes. Unlike meningiomas that grow on the outside of the brain and compress inward, gli
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For over 60 years, we thought metformin worked mainly through the liver and gut. But new research suggests the brain may play a major role too. This study identified a specific brain pathway (Rap1 in the hypothalamus) that appears critical to metformin’s glucose-lowering effects, potentially reshaping how we understand one of the world’s most prescribed diabetes medications. Source: Sci. Adv. 2025;11:eadu3700
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Not All Brain Tumours Are Cancerous
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