An unusually 'sticky' RNA class that keep cells organized: Researchers discover smOOPs

Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential ...

DNA transcription is a tightly choreographed event: How RNA polymerase II regulates the dance

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...
Nature

We are all mosaics: vast genetic diversity found between cells in a single person

Technical advances allow researchers to trace the genetic changes that occur over time.

Growing human organs for medical implants: New method gives human stem cells an edge in chimeric embryos

Scientists have discovered a method of helping human stem cells thrive in an animal embryo—a key development in efforts to ...
Labroots

RNA Processing Seems to Affect Lifespan

When a gene is expressed, its DNA sequence is transcribed into a molecule known as RNA. Then the cell processes and edits ...
AlphaGalileo

New RNA Class Discovered that Helps Keep Cells Organized

Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential ...

New insight into how protein TDP-43 affects gene expression in ALS and FTD

Neurodegenerative diseases, such as Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and frontotemporal dementia ...
News-Medical.Net on MSN

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell ...
News-Medical.Net on MSN

Discovery of smOOP RNAs reveals hidden rules of cellular phase separation

Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential for organizing cellular life, yet why some RNAs cluster more readily than ...
ZME Science on MSN

This 39,000-Year-Old Mammoth Holds the World’s Oldest Preserved RNA

RNA usually breaks down quickly, often within hours after death. Before this study, the oldest recovered RNA came from a ...
eLife

TSvelo: Comprehensive RNA velocity by modeling the cascade of gene regulation, transcription and splicing

This study presents a valuable tool named TSvelo, a computational framework for RNA velocity inference that models transcriptional regulation and gene-specific splicing. The evidence supporting the ...

Certain immune cell subtypes drive lupus, study finds

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell ...