The Kowalinski group at EMBL Grenoble discovered notable differences between the nuclear cap-binding complex in trypanosomes and humans, a critical component in cellular RNA metabolism. Trypanosomes ...

Trypanosomes are parasites that cause sleeping sickness, Chagas disease, and various animal diseases. Diagnosis and treatment ...

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA.

Enzymes made of RNA are called "ribozymes." A group of researchers led by Professor Claudia Höbartner at the University of ...

Both intext and exercise questions are important for students from the perspective of 2025 examination. Solving these ...

The current human tissue-based study provides convincing evidence correlating hippocampal expressions of RNA guanine-rich G-quadruplexes with aging and with Alzheimer's Disease presence and severity.

Structure: DNA is composed of two long chains of nucleotides forming a double helix. The nucleotides within each strand are joined together through covalent (specifically phosphodiester) bonds between ...

The structure with the largest pocket (i.e. largest distance ... 8bp blunt-ended RNA (B) 8bp RNA with two nucleotide overhangs on 3’ ends (C) 25bp blunt-ended RNA (D) 25bp RNA with two nucleotide ...

No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like AlphaFold remain unavailable for RNA, creating a critical gap in ...