DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

In conclusion, in-cell SHAPE-MaP enables RNA structure to be examined at single-nucleotide resolution in a native cellular environment, including for RNAs of low to moderate abundance.

SCOPER has simplified it significantly. Say you want to study a new RNA: First, put the nucleotide sequence into one of the open-source, AI-based structure prediction tools available today.

Researchers describe a way to use AI to reliably predict the structure of certain RNA molecules from their nucleotide sequence in the journal <i>PLOS Computational Biology</i>.

Negotiating the twists and turns of RNA promises to become easier, thanks to new techniques such as in-gel analysis, sequencing, mapping, and nanoassembly.

New app shows 2-D structure of thousands of RNA molecules Date: September 2, 2010 Source: Stanford University Medical Center Summary: For the first time, it's possible to experimentally capture a ...

To understand what an individual RNA molecule does, its 3D structure needs to be deciphered at the level of its constituent atoms and molecular bonds. Technology used to study the structures of ...

RNA's fate is determined by chemical modifications that affect its stability, structure and interactions and thereby its fate. More than 170 distinct RNA modifications have been described thus far.

More than 170 distinct RNA modifications have been described so far. The most abundant is the methylation on the N6-position of the RNA-nucleotide adenosine (m6A).