RNA molecules are an integral part of the human body: In cells, they ensure the transfer of genetic information and regulate the activity of genes. Some even act as catalysts, allowing chemical ...
Small, biologically inert molecules can be converted into bioactive degraders that selectively downregulate disease-causing RNAs. By attaching an RNA molecular recognition element to a second compound ...
Molecular geneticists describe ways to develop the -- as yet largely untapped -- potential of RNA structures. The human genome has just over 20,000 genes coding for proteins. Yet, it produces at least ...
In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read like a recipe to build a protein. But there's more to the story. Some RNA ...
Crystal structure of the NHL domain of mouse TRIM71 complexed with a stem-loop structured Trincr1 RNA motif. Detailed interactions between key residues of TRIM71 and Trincr1 RNA are shown in an ...
Two new research papers from the Living Brain Project at Mount Sinai present what is, by several metrics, the largest ...
xFOREST Therapeutics Co., Ltd. (“xFOREST”) and Axcelead Drug Discovery Partners, Inc. (“Axcelead DDP”) today announced the launch of a joint research collaboration aimed at developing RNA ...
Bacteriophages, or phages for short, are viruses that infect bacteria. Using phages therapeutically could be very useful in fighting antibiotic-resistant pathogens, but the molecular interactions ...
The human body has to protect itself from pathogens and infectious agents, and there are a variety of ways for the immune system to sense foreign invaders, and react to the threats they may pose. But ...
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