Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published in The EMBO Journal shows that the cells deliberately slow the activity of their ...

Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published today in The EMBO Journal shows ...

Scientists have discovered how a key protein helps maintain strong connections between brain cells that are crucial for ...

The 26S proteasome, which is a central element of the UPS, comprises one or two 19S regulatory particles and a barrel-shaped catalytic core called 20S proteasome or core particle (CP). The 19S module ...

Data suggest that “venetoclax usage should be avoided in the general relapsed or refractory multiple myeloma population,” the researchers wrote.

The Food and Drug Administration (FDA) has granted accelerated approval to Lynozyfic™ (linvoseltamab-gcpt) for the treatment of adult patients with ...

The FDA approved Lynozyfic (linvoseltamab-gcpt) to treat adults with relapsed/refractory multiple myeloma who have received at least 4 prior lines of therapy.

Regeneron Pharmaceuticals, Inc. REGN obtained FDA approval for linvoseltamab-gcpt for the treatment of relapsed or refractory ...

Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that the U.S. Food and Drug Administration (FDA) has granted accelerated approval for Lynozyfic™ (linvoseltamab-gcpt) to treat adult ...

In mammals, the 19S regulator contains multiple ubiquitin binding sites, which regulate the proteasome conformation that activates unfolding, deubiquitination, and degradation of various protein ...