SUMO E1 inhibition inhibits ocular lens fibrosis by suppressing TGFβ2-induced SMAD4 SUMOylation Fibrotic cataracts are a ...

Two mutated alleles of the cystic fibrosis transmembrane conductance regulator (CFTR) gene result in the autosomal recessive ...

Frozen shoulder is more common during perimenopause and menopause, likely due to changes in estrogen. Early diagnosis, physical therapy, lifestyle habits, and anti-inflammatory treatments can support ...

Liver fibrosis is the buildup of scar tissue in the liver, the organ that helps you digest food, store energy, and remove toxins. Liver fibrosis occurs as the organ tries to repair itself from ...

Protein clustering mechanism on the cell membrane presents a new therapeutic target for cystic fibrosis. A new study from The Hospital for Sick Children (SickKids) reveals the process underlying ...

Breathing disorders are common in the U.S. with conditions like COPD affecting some 7% of the population and asthma affecting another 10%. Digestive conditions like GERD, acid reflux, Celiac disease ...

Background Lymphatic malformations (LMs) are low-flow, congenital lesions commonly presenting as asymptomatic masses in the head and neck. However, large lymphangiomas can significantly affect ...

Please provide your email address to receive an email when new articles are posted on . Inflammation is associated with every surgical procedure. In most surgical specialties, postoperative ...

The authors declare no conflicts of interest. The patient has given informed consent to the publication of their case details. Jaccoud’s hand is a rare deforming arthropathy, first described in 1869 ...

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