Emerging evidence suggests a role for PI3K/mTOR signalling in the pathology of organ fibrosis. The aim of this study was to delineate PI3K/mTOR signalling in response to TGF-β 1 stimulation of primary ...

Introduction Symptoms of breathlessness in people referred to a Tertiary Airways and Severe Asthma service may be due to a variety of treatable conditions, including asthma, inducible laryngeal ...

Correspondence to British Thoracic Society, 17, Doughty Street, London WC1N 2PL, UK; bts{at}brit-thoracic.org.uk and Dr Charlotte E Bolton, Nottingham Respiratory Research Unit, University of ...

Department of Critical Care and Department of Medicine, St Michael's Hospital, Interdepartmental Division of Critical Care, University of Toronto, Toronto, Ontario, Canada Correspondence to: Dr A S ...

History of Medicine Department, Medical School, University of Athens, Athens, Greece Correspondence to Dr Marianna Karamanou, History of Medicine Department, Medical School, University of Athens, 4 ...

Department of Human Biology, Nutrition and Toxicology Research Institute (NUTRIM), Maastricht University, Maastricht, The Netherlands Dr A M W J Schols, NUTRIM School for Nutrition, Toxicology and ...

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Jewish Health, Denver, Colorado, USA Background: While acute lung injury (ALI) is among the most serious ...

Non-specific bronchial reactivity is related to the severity of clinical asthma. Histamine challenge testing is increasingly used in association with questionnaires in epidemiological studies of the ...

12 Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada Correspondence to Dr Wan C Tan, UBC James Hogg Research Centre, Providence Heart+Lung Institute, University of ...