RMD Open

Early-life animal and farming exposures and the risk of rheumatoid arthritis: findings from the E3N French cohort study

Objective The objective of this study is to assess the association between childhood exposure to pets and farm animals and ...
RMD Open

Long-term outcomes of JIA-associated uveitis: a systematic review and meta-analysis

Background and aim Juvenile idiopathic arthritis-associated uveitis (JIAU) is a potentially blinding condition beginning in ...
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Automated ultrasound in rheumatology: the dawn of a new era

Diagnosis made with an imaging technique is the result of two mainly sequential, variously and closely intertwined processes: image acquisition and image interpretation. These two processes may be ...
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Upadacitinib in patients with psoriatic arthritis and an inadequate response to non-biological therapy: 56-week data from the phase 3 SELECT-PsA 1 study

Background In SELECT-PsA 1, a randomised double-blind phase 3 study, upadacitinib 15 mg and 30 mg were superior to placebo and non-inferior to adalimumab in ≥20% improvement in American College of ...
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Complement system activation is associated with spinal radiographic progression in axial spondyloarthritis after 2 years of follow-up: findings from the CONSUL RCT

Objective To investigate complement system activation and complement protein levels in relation to radiographic progression in axial spondyloarthritis (axSpA) within a longitudinal randomised ...
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Synovial fibroblast activation occurs before the onset of rheumatoid arthritis and influences the risk of developing disease

Objectives Activated synovial fibroblasts play a key role in rheumatoid arthritis (RA). Positron emission tomography-CT (PET-CT) using 68g allium-labelled fibroblast activation protein inhibitor (FAPI ...
rmdopen.bmj

Adenosine metabolic signature in circulating CD4+ T cells predicts remission in rheumatoid arthritis

Objectives Long-term outcomes in rheumatoid arthritis (RA) depend on early and effective disease control. Methotrexate (MTX) remains the first-line disease modifying therapy, however there are no ...
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Identification of individuals at high risk of developing rheumatoid arthritis: a balanced random forest model in a cohort of 1544 first-degree relatives

Objectives To identify in a genetically susceptible population individuals at higher risk of developing rheumatoid arthritis (RA) using a classification approach combining known epidemiological risk ...
rmdopen.bmj

Optical coherence tomography angiography detects retinal microvascular changes in giant cell arteritis: the potential protective role of aortitis

Objectives To evaluate the diagnostic utility of optical coherence tomography angiography (OCTA)-derived biomarkers in patients with giant cell arteritis (GCA) and to advance the pathophysiological ...
rmdopen.bmj

Diagnostic performance and reliability of robotic ultrasonography and artificial intelligence-driven synovitis assessment in rheumatoid arthritis: results from the Controlled ...

Aim To evaluate the reliability and diagnostic performance of artificial intelligence (AI) driven robotic ultrasonography (RUS) compared with human ultrasonography (HUS) performed by a trained ...
rmdopen.bmj

Inflammatory rheumatic diseases with onset after SARS-CoV-2 infection or COVID-19 vaccination: a report of 267 cases from the COVID-19 and ASD group

Objectives To better define the spectrum of new-onset post-COVID-19 and post-COVID-19 vaccine inflammatory rheumatic diseases (IRD) from a large multicentric observational study. Methods Consecutive ...