Root canal anatomical variations are common, but a two-rooted maxillary central incisor with a concomitant labio-radicular groove is rare. The presence of this groove may result in challenges for ...

A woman in her early 40s with symptomatic subaortic membrane and severe left ventricular outflow tract (LVOT) obstruction underwent subaortic membrane resection with limited septal myectomy via median ...

A woman in her late 30s presented after an out of hospital cardiac arrest secondary to ventricular fibrillation. She received cardiopulmonary resuscitation with a mechanical device. In the emergency ...

Insulinomas are rare functioning pancreatic neuroendocrine tumours and are exceptionally uncommon in childhood. We report an adolescent boy with a 4-year history of recurrent episodes of loss of ...

Erdheim-Chester disease (ECD) is a rare histiocytic neoplasm with cardiovascular involvement that is often under- or misdiagnosed. We report a male in his 30s presenting with dyspnoea and anasarca.

Reversible cerebral vasoconstriction syndrome (RCVS) is an uncommon neurovascular complication reported with Guillain-Barré syndrome (GBS). A woman in her 30s developed rapidly progressive ...

Fetal intraventricular haemorrhage is a rare condition with heterogeneous causes. We report severe congenital protein C deficiency (SCPCD) in a neonate with a previous sibling who had a similar ...

Combination immune checkpoint inhibitor and tyrosine kinase inhibitor therapy is standard in advanced clear cell renal cell carcinoma (RCC). While tumour lysis syndrome (TLS) is well recognised in ...

Pregnancy in women with systemic lupus erythematosus is associated with increased risk of disease flares and adverse maternal and fetal outcomes. Therapeutic options during pregnancy remain limited, ...