Ribosome ubiquitination regulates HAC1 mRNA processing during the unfolded protein response. Here, the authors show that the SCFGrr1 complex promotes HAC1 mRNA splicing and translation by ...

Scientists have uncovered a critical piece of the puzzle in autoimmune diseases: a protein that helps release immune response ...

Researchers found that ArfGAP2 appears to play a key role in both normal immune responses and harmful overactivity.

Proteins are long molecules that must fold into complex three-dimensional structures to perform their cellular functions. This folding process occasionally goes awry, resulting in misfolded proteins ...

Subscribe for FREE “For most proteins, we model the folding process as if there are two states, folded or unfolded,” said Yang Jiang, assistant research professor of chemistry in the Eberly College of ...

For the first time, scientists have identified promising drug candidates that bind irreversibly with a notoriously ...

Our cells harbor a DNA detector termed cGAS to inform the immune system of viral and bacterial infections, cell death, as ...

Scientists have discovered a protein that enables bacteria to shut down into dormant spores under extreme conditions. The process, which enables the bacteria to become practically indestructible, ...

A research team has uncovered new insights into the molecular mechanisms of ADAR1, a protein that regulates ribonucleic acid (RNA) induced immune responses. Their findings could open new pathways for ...

Cellular reprogramming is an intrinsic evolutionary trait to constantly promote adaptations that confer survival advantage.

As Nigel Farage and his supporters prepared for their 11pm party in Parliament Square to celebrate Britain’s departure from the EU, reports of two Chinese nationals testing positive for ...