For the past half-century, structural biologists relied on the notion that similar protein sequences give rise to similar structures and functions. While this assumption has driven research to explore ...

Alternative splicing affects more than 95% of multi-exon genes in the human genome. These changes affect the proteome in a myriad of ways. Here, we review our understanding of the breadth of these ...

The Max Planck Institute of Colloids and Interfaces (MPICI) has created a carbohydrate sequence that can fold into a stable secondary structure. To date, self-folding biopolymers had only been ...