Delve into the increasingly dynamic landscape of ALS treatment development with thirteen companies advancing candidates in ...
The Kowalinski group at EMBL Grenoble discovered notable differences between the nuclear cap-binding complex in trypanosomes and humans, a critical component in cellular RNA metabolism. Trypanosomes ...
In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.
A new study from the Kowalinski group at EMBL Grenoble characterized the structure of an important trypanosomal protein ...
Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...
Genetics Lab to study the function of U6 snRNA modifications in RNA splicing in human cancers. Pre-mRNA splicing is carried out by the spliceosome which contains more than 100 proteins and 5 U snRNAs.
The FDA has granted fast track designation to DYNE-101, a therapy for myotonic dystrophy type 1 (DM1) now in testing in a ...
RNA (ribonucleic acid ... Here, the authors provide insights into a splicing quality control mechanism. The Gpl1–Gih35 complex binds to the active site of aberrant spliceosomes, blocks splicing ...
Studies of living participants and postmortem brains confirm that gene expansion is a promising target for HD prevention ...
After hours: January 22 at 6:10:10 PM EST Loading Chart for RNA ...