The Kowalinski group at EMBL Grenoble discovered notable differences between the nuclear cap-binding complex in trypanosomes and humans, a critical component in cellular RNA metabolism. Trypanosomes ...

A new study from the Kowalinski group at EMBL Grenoble characterized the structure of an important trypanosomal protein ...

In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

Delve into the increasingly dynamic landscape of ALS treatment development with thirteen companies advancing candidates in ...

A study published in PNAS reveals how a bacterial pathogen coordinates N-acetylneuraminic acid (Neu5Ac) metabolism at the ...

Researchers have determined the 3D structure of SAMURI, an artificial ribozyme that precisely modifies RNA. Using ...

A study reveals how Salmonella enterica leverages a small RNA, ManS, to regulate Neu5Ac metabolism and adapt to the host ...

A research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other neurodegenerative disorders such as ...

This study not only discovered a novel 3′ UTR-derived sRNA but also expanded the understanding of RNase III-mediated RNA processing. It highlights the critical role of ManNAc in bacterial ...

Scientists at the University of California, Irvine, have discovered that nuclear speckles, a membraneless organelle within ...