DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

A strategy that analyzes the structural properties of RNA could help identify regions that are promising targets for antiviral drugs.

Say you want to study a new RNA: First, put the nucleotide sequence into one of the open-source, AI-based structure prediction tools available today. Then, take your sample to a small angle X-ray ...

Computational predictions of biomolecular structure via artificial intelligence (AI) based approaches, as exemplified by AlphaFold software, have the potential to model of all life’s biomolecules. We ...

DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

I investigated whether base reactivities and secondary structure models derived from them can explain some variability in the frequency of observing different nucleotide substitutions across millions ...

Choose from 1,423 Nucleotide stock illustrations from iStock. Find high-quality royalty-free vector images that you won't find anywhere else.

RNA's fate is determined by chemical modifications that affect its stability, structure and interactions and thereby its fate. More than 170 distinct RNA modifications have been described thus far.

More than 170 distinct RNA modifications have been described so far. The most abundant is the methylation on the N6-position of the RNA-nucleotide adenosine (m6A).

RNA is involved in a vast number of biological processes that are central to life, and its structure is quite diverse in terms of nucleobase structure (over 120 modified nucleobases), molecule size ...