In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

Biologically active RNAs, including transport, ribosomal and small nuclear RNA (tRNA, rRNA, snRNAs) fold into unique structures guided by complementary pairing between nucleotide bases.

Both intext and exercise questions are important for students from the perspective of 2025 examination. Solving these ...

The structure with the largest pocket (i.e. largest distance ... 8bp blunt-ended RNA (B) 8bp RNA with two nucleotide overhangs on 3’ ends (C) 25bp blunt-ended RNA (D) 25bp RNA with two nucleotide ...

Structure: DNA is composed of two long chains of nucleotides forming a double helix. The nucleotides within each strand are joined together through covalent (specifically phosphodiester) bonds between ...

To cap the RNA product, m7G(5’)ppp(5’)G RNA Cap Structure Analog (New England Biolabs ... GC content, the ratio of G/C nucleotide of a sequence, and short kmer (k=1∼3) were calculated by ...

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA. Researchers ...

In cells, they ensure the transfer of genetic information and regulate the activity of genes. Some even act as catalysts, ...

No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like AlphaFold remain unavailable for RNA, creating a critical gap in ...