To prevent this, cells have developed a sophisticated system to mark unwanted proteins for degradation with a small protein called ubiquitin. Ubiquitin chains Ubiquitin is a cellular tag that marks ...

Researchers sought to determine the significance of short-term blood pressure variability for assessing CTR-CVT in patients with multiple myeloma undergoing treatment with proteasome inhibitors.

SHANGHAI, March 19, 2025 /PRNewswire/ -- CARsgen Therapeutics Holdings Limited (Stock Code: 2171.HK), a company focused on ...

Orphan Drug Designation follows positive Phase 1 data presented at the 12th International Workshop on Waldenström Macroglobulinemia. First-in-class Bruton’s tyrosine kinase (BT ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

Believe it or not, we’re just three months away from the announcement of iOS 19. Ahead of that launch, rumors about new iOS 19 features, supported devices, and more have started to surface.

We expect to see the iOS 19 unveiled at the upcoming WWDC'25 developer conference, which should take place in early June 2025. An early developer beta should be made available during WWDC. Like the ...

The cellular waste disposal system called the proteasome is best known for its central role in protein degradation and recycling, but as far back as the 1990s it was shown that products of this ...

The No. 15-ranked Missouri Tigers kept their pedal on the gas in their regular season finale against No. 19 Kentucky, but failed to catch up after the Wildcats outpaced the Tigers in the first half.

Hearts and Hibs are represented in the Scotland Under-19 squad for an upcoming double header of friendly fixtures. After overseeing five wins in his first eight matches in charge, former Hearts ...

One of the key elements of that system is the proteasome, a structure that chops up proteins that are faulty or no longer needed into smaller pieces known as peptides. These fragments might be ...