The sensitive identification of single nucleotide polymorphisms becomes increasingly important for disease diagnosis, prevention, and practical applicability of pharmacogenomics. Herein, we propose a ...

A strategy that analyzes the structural properties of RNA could help identify regions that are promising targets for antiviral drugs.

VAV1 is a guanine nucleotide exchange factor essential for T- and B-cell receptor signaling, with expression largely restricted to immune cells. Loss of VAV1, via CRISPR or genetic deletion, impairs ...

Organ transplantation has significantly revolutionized the treatment of patients with organ failure. However, the recipient's immune system recognizes transplanted organs as foreign and elicits a ...

ProQR Announces CTA Submission for Phase 1 Study of AX-0810 Targeting NTCPFirst-in-human trial of AX-0810 will evaluate safety, tolerability, pharmacokinetics, and target engagement in healthy ...

Advancements in array technology, such as single nucleotide polymorphism (SNP) arrays and combined CNV + SNP platforms, are improving diagnostic yield and enabling more comprehensive genomic analysis.

There's a strong case that healthcare is the most important sector in the stock market. Investors stand to benefit as ...

A research team led by the University of the Basque Country has identified hundreds of molecular markers in saliva that could ...

Alignment and sequencing errors are a major concern in molecular evolution, and this valuable study represents a welcome improvement for genome-wide scans of positive selection. This new method seems ...

Researchers at Shanghai Jiao Tong University have produced fertile adult mice from embryos constructed entirely with male ...