The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...

This enzyme is able to silence specific DNA sections by epigenetically modifying histone proteins that package the DNA. These modifications ensure that the DNA is densely packed as heterochromatin ...

Replication-dependent histone mRNAs, which encode the most abundant histone proteins, are the only known cellular mRNAs that are not polyadenylated. Instead they end in a conserved stem–loop ...

Short-chain fatty acids (SCFAs) like propionate and butyrate are critical byproducts of dietary fiber digestion. These ...

Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer ...

Researchers uncover a link between genetic mutations and epigenetic changes, two major contributors to aging. Their findings ...

Researchers studied mice on a fibre-rich diet and found that gut bacteria influence gene regulation through short-chain fatty ...

Dopamine, serotonin, and histamine carry messages between neurons. They can also influence circadian gene expression ...

The teams found that TG2 acts as a regulator of intracellular monoamine neurotransmitters with an ability to not only add monoamines to histone H3 but also erase and exchange one monoamine ...

Epigenetic modifiers, enzymes that catalyze covalent modifications on chromatin, play a pivotal role in establishing stable ...

This enzyme is able to silence specific DNA sections by epigenetically modifying histone proteins that package the DNA. These modifications ensure that the DNA is densely packed as heterochromatin ...