Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...

Segmental copy-number gains are major contributors to human genetic variation and disease, but how these alterations arise remains incompletely understood. Here, based on the analyses of both ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

Cancer is a major topic of controversy for the international community. However, there is currently no known therapy for cancer, and progress in cancer treatment is still in the interest of ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...

Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...