Azole-6-nitro-[1,5-a]pyrimidine, a promising energetic building block, was rationally designed and efficiently synthesized via an aqueous synthetic route. Employing this versatile precursor, three ...

The randomised global study achieved its primary endpoint.

Scientists rarely expect to find drug resistance in places that are untouched by drugs. The Three Parallel Rivers region of Yunnan, China, sits high in the Eastern Himalayas, far from clinics, farms, ...

A virus-resistant winter wheat variety is showing promising results on the South Downs in Hampshire producing a good milling ...

The study achieved the primary endpoint of non-inferiority, with a rate of all-cause mortality (ACM) at Day 42 for olorofim of 23.8% and for ...

Timber Specialties Limited, the Canadian wood preservative division of Koppers Inc., is pleased to announce the launch of ...

After years of antifungal resistance increasingly making standard-of-care treatments less effective, F2G and Shionogi have ...

Maintenance revumenib was restarted post SCT at the pretransplant dose with azole-based adjustments across monotherapy, combination-trial, and expanded-access settings in genetically defined ...

The U.S. FDA’s Vaccines and Related Biological Products Advisory Committee (VRBPAC) is deliberating the merits of Moderna Inc.’s mRNA influenza vaccine, mRNA-1010, which the company wants to brand ...

Just under Earth’s surface, 110 quadrillion kilometres of carbon-rich fungi intersect with plant roots. This vast network has been laid bare in the first global digital map of our planet’s mycelial ...

The environmental use of azole fungicides has led to selective sweeps across multiple loci in the Aspergillus fumigatus genome causing the rapid global expansion of a genetically distinct cluster of ...

Neural stem cells are multipotent adult stem cells present in the adult central nervous system that can self-renew, and give rise to new neurons and supporting cells called glial cells. Activation of ...