Shares of 2seventy bio, Inc. TSVT gained 5.26% after the company announced a definitive merger agreement with Bristol Myers Squibb BMY. Per the terms of the deal, BMY will acquire all of the ...

Shares of 2seventy bio, Inc. TSVT gained 5.26% after the company announced ... including an immunomodulatory agent, a proteasome inhibitor and an anti-CD38 monoclonal antibody.

This Patent Highlight showcases the development of novel small-molecule inhibitors for KRAS and CDKs ... tagging the target for degradation by the proteasome. These compounds enable the selective ...

The Soviet-era An-26 first flew in 1969 and the order – listed in procurement documents, according to news agency Interfax – would extend the type’s life from 50 years to 60.

A new part of the immune system has been discovered and it is a goldmine of potential antibiotics, scientists have said. They've shown a part of the body known to recycle proteins has a secret ...

To test this hypothesis, the researchers infected human cells with the bacterium Salmonella typhimurium, and some of the human cells were treated to inhibit the proteasome. Inhibition of the ...

The cellular waste disposal system called the proteasome is best known for its central role in protein degradation and recycling, but as far back as the 1990s it was shown that products of this ...

Pathological cardiac hypertrophy is the abnormal enlargement of the heart muscle in response to chronic stressors such as hypertension, myocardial infarction, or valvular disease. This maladaptive ...

Protease inhibitor cocktail (complete ... Silver staining was performed with SilverSNAP kit II (Pierce/Thermo). 26S proteasome activity in cell extracts was measured by a proteasome activity kit ...