A new layer of the human genome: Embedded RNA marks may reshape DNA twisting

A new study led by Francesca Storici, a professor in the School of Biological Sciences and faculty member of the Parker H.

Scientists discover hidden layer of RNA that helps fine-tune how tightly DNA coils itself

Researchers mapped RNA fragments embedded in human DNA, revealing a new genomic layer called the "ribome" that may shape gene ...
Science Daily

Life uses 4 DNA letters. Scientists just made 8 work

Researchers at UC San Diego have demonstrated that a key cellular enzyme can accurately read an eight-letter genetic alphabet ...

RNA creates a self-destruct switch for cellular machinery linked to leukemia

Cells have all kinds of intricate machinery to control genes, switching them on and off at the right times and under the ...
The Scientist

CRISPR’s Ability to Knock Down RNA May Be Artificially Inflated

Researchers testing out CRISPR systems found that their ability to disrupt gene expression was artificially enhanced by an ...
Phys.org

The RNA revolution: How our understanding of life's blueprint is being rewritten

For decades, the central dogma of molecular biology—DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease. This model explained ...
Technology Networks

RNA Polymerase Can Read and Transcribe an Expanded Genetic Alphabet

Researchers showed that E. coli RNA polymerase can accurately recognize and transcribe two synthetic base pairs, supporting ...

An RNA molecule contributes to therapy resistance of triple negative breast cancer

Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer. Chemotherapy before or after surgery ...