Foamy virus (FV) vectors are an alternative type of retroviral vector with a large packaging capacity, 16 wide host range, 17 and a complementary DNA genome. 18, 19 FV vectors may be less oncogenic ...
A variety of mutations in lentiviral vector expression systems have been shown to generate a non-integrating phenotype. We studied a novel 12 base-pair U3-long terminal repeats (LTR) integrase (IN) ...