A new class of microscopic machines is moving from theory into reality, and it could change how diseases are treated and how ...

Antibodies are like "guided missiles" that find and attack cancer cells, but cancer-causing mutations inside cells have ...

Researchers at the University of Illinois Chicago have identified a molecular switch that helps determine whether cancer ...

A new lipid nanoparticle platform delivers full-length antibodies inside cells, unlocking intracellular targets in cancer, ...

Potent drugs like chemotherapy can be life-saving, but often with life-threatening side effects. Notably, they can be indiscriminate, killing both cancer cells and healthy cells in one swoop.

Drug-delivering aptamers that can precisely target leukemia stem cells with enhanced potency have been developed. Delivering anticancer drugs with specificity and potency to cancer stem cells is an ...

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers report. The aptamers -- short ...

Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers like leukemia and lymphoma. But the immunotherapy has struggled against solid tumors for two ...

Cell-free systems, which can express an easily detectable protein with a DNA or mRNA template without constraints of living cells, are attractive as foundations for biosensors. Moreover, by ...