A new study shows that RNA splicing, not just gene expression, holds powerful clues to why some mammals live far longer than ...

When a gene is expressed, its DNA sequence is transcribed into a molecule known as RNA. Then the cell processes and edits ...

A study captured the first near frame-by-frame view of a self-splicing ribozyme assembling into its active form. Using ...

A study across 26 mammals reveals that alternative RNA splicing strongly correlates with maximum lifespan. Brain tissue ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function ...

This study presents a valuable tool named TSvelo, a computational framework for RNA velocity inference that models transcriptional regulation and gene-specific splicing. The evidence supporting the ...

The W.M. Keck Foundation awarded a $1.2 million grant to medicinal chemistry and computational biology researchers at the University of Kansas (KU) and the University of Chicago focused on finding ...

RNA splicing involves the removal of non-coding introns and the joining of coding exons in precursor mRNA (pre-mRNA) to produce mature messenger RNA (mRNA). Splicing changes can lead to diseases, ...

Scientists have created a model to study the role of RNA splicing defects in Alzheimer's disease, revealing degeneration and toxicity caused by neuron hyperexcitability. Researchers have puzzled over ...