What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms. Next, the snRNPs U2 and U4/U6 appear to ...

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

A research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other neurodegenerative disorders such as ...

A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington’s disease and link HD with other ...

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...

Novel paradigm for therapeutics based on RNA splicing modulation Lead program in Huntington’s disease Denmark – Odense – 07/01/2025 – Inverna Therapeutics, a novel Danish biotech company at the ...

Utilizing invaluable tissue samples from global brain banks, the study sheds light on a process essential for accurate RNA splicing—a cornerstone of proper gene expression. The researchers ...

Working at the interface of RNA splicing and breast cancer biology, our current focus is on regulation of breast cancer metastasis driven by alternative splicing. We use molecular biology, genomics, ...

The realization that most human genes generate multiple mRNAs encoding divergent protein isoforms via alternative splicing and polyadenylation has revealed extensive regulation that remains to be ...

In this webinar, Dr. Megan L Noonan will present her research on the role of alternative splicing in kidney disease progression, discussing how she used nanopore RNA sequencing to accurately detect ...