How oligodendrocytes use fatty acid metabolism as an energy reserve to maintain axonal function and myelin stability when glucose is scarce, offering insights into neurodegenerative disease mechanisms ...

Nerve fibers in the brain and spinal cord are wrapped in an insulating sheath known as myelin. For a long time, this barrier, which is essentially the brain's white matter, was believed to serve the ...

Scientists have always presumed that the Aβ in plaques comes solely from neurons. Three recent papers challenge that assumption, identifying another, unexpected source—oligodendrocytes. In the ...