The simultaneous silencing of NUMB and HDM2 restored p53 to levels indistinguishable from that of control cells or HDM2-KD cells (Fig. 2d). Nutlin stabilizes and activates p53 (ref. 21). Nutlin ...

Your lips are among the most touch-sensitive parts of your body. But suddenly, they’ve gone numb and rubbery — a bit like when your foot or arm falls to sleep. What gives? Numbness in your lips means ...

You may have heard of sleep paralysis but numbness in hands and feet while sleeping is another common problem experienced by many people. This condition may be temporary, but if it happens frequently, ...

When it's extra cold outside, even if you remember your gloves or mittens, your fingers are always the first things to go numb. In this case, that's due to a process called vasoconstriction, in which ...