Since the identification of the first SCN5A mutation associated with long QT syndrome in 1995, several mutations in this gene for the α subunit of the cardiac sodium channel have been identified in a ...

The study from St. Jude Children's Research Hospital presents a new understanding of how a VGIC, crucial for the communication of neurons and muscle cells, can become unresponsive. Scientists at St.

Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal 'firing' in the central nervous system and for brain and heart function. These channels use a ' ...

image: From left to right, Dr. Chia-Hsueh Lee and Dr. Hongtu Zhao of the Department of Structural Biology at St. Jude Children's Research Hospital. Dr. Lee and Dr. Zhao are co-authors of a new study ...