Background: Diagnosis of monoclonal gammopathies (MGs) is determined by demonstration of a monoclonal immunoglobulin molecule or chain in serum and/or urine. Previous results on immunofixation ...

A 41-year-old male with IgG kappa multiple myeloma is described. He developed a free gamma heavy chain without an accompanying light chain following high-dose chemotherapy and autologous peripheral ...

Heparin-induced thrombocytopenia (HIT) is an immune-mediated platelet disorder caused by antibodies that target complexes of platelet factor 4 (PF4) and heparin. HIT has been characterized as a ...

Current guidelines by the International Myeloma Working Group and College of American Pathologists recommend performing serum protein electrophoresis (SPEP) and serum free light chain (sFLC) testing ...

A series of tests physicians routinely order to help diagnose and follow their patients with an elevated antibody level that is a marker for cancer risk, often do not benefit the patient but do ...

AUGUSTA, Ga. (July 13, 2018) -When it comes to diagnosing a condition in which the plasma cells that normally make antibodies to protect us instead become cancerous, it may be better to look at the ...

In the recent Leukemia article, Laubach et al describe the International Myeloma Working Group's recommendations for the evaluation and treatment of relapsed multiple myeloma. Importantly, the ...

Urine immunofixation is a test that measures proteins in your urine. It specifically looks for monoclonal protein, or M-protein, which shouldn’t be there in most cases.‌ Doctors will be able to find ...

Clin Lymphoma Myeloma. 2010;10(4):278-280. Our study has several limitations. Clinical information on the patients studied was incomplete, in part because half of the serum specimens came from ...