This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

Genomic DNA is wrapped around histone octamers to provide nucleosomes that are further compacted in chromatin fibers. To up-regulate a gene (a), the activator binds to a specific sequence and recruits ...

MAbID offers new insights into how these mechanisms work together or against each other. The results were published in Nature Methods on the 4th of December. DNA is the most important carrier of ...