The human brain constantly adapts in response to experiences, forming new connections between neurons and reorganizing ...

"It's not intuitive to think the most prevalent receptor for the major neurotransmitter in the brain is also present in the lens," senior investigator Peter Frederikse, PhD, from the University of ...

Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...

Metabotropic glutamate receptors (mGluRs) are a family of G protein-coupled receptors that modulate excitatory neurotransmission and intracellular signalling pathways throughout the central nervous ...

Researchers use cryo-EM to reveal how the NMDA receptor's Asn cage filters calcium from magnesium to drive learning and memory.

The most common type of brain tumor in children, pilocytic astrocytoma (PA), accounts for about 15% of all pediatric brain tumors. Although this type of tumor is usually not life-threatening, the ...

In the intricate chemical symphony of the brain, glutamate stands as the principal conductor. As the brain's most abundant excitatory neurotransmitter, glutamate facilitates our ability to learn, form ...

Neurotransmitters are the words our brain cells use to communicate with one another. For years, researchers relied on tools that provided limited temporal and spatial resolution to track changes in ...