When the TREX1 gene is functioning normally, it produces a protein that helps maintain DNA in cells throughout the body. Mutations in the TREX1 gene are known to cause a rare and serious disease ...

Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth.

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth ...

Study results indicate that mutation strength may shape both tumor–immune system interactions and immunotherapy response.

Patients with CaV2.1 channelopathies face severe and often debilitating symptoms, such as seizures, migraines, tremors, and developmental delays. Although some symptoms overlap among these rare ...

A study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, reveals why a specific gene mutation behaves differently from other variants. Subscribe to our newsletter ...

LONDON, Oct 23 (Reuters) - Scientists have uncovered a second gene mutation that determines which patients will respond to the bowel cancer drugs Erbitux and Vectibix, opening the way to still more ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumour ...

While men may be able to have children much later than women, doing so could come with an increased risk of inherited disease for their children. Researchers from the Wellcome Sanger Institute have ...