Cellular metabolism relies on a finely tuned network of transport systems that govern the movement of ions, metabolites and signalling molecules across biological membranes. These systems include ...

Researchers are able to test in parallel the effects of over 1500 active substances on cell metabolism. Their analysis also led to the discovery of previously unknown mechanisms for known medications.

In a scientific first, researchers from Vanderbilt University and the University of California, San Diego, have generated a high-resolution metabolic "map" of how cells orchestrate glucose processing, ...

Understanding how cells process nutrients and produce energy - collectively known as metabolism - is essential in biology. However, analyzing the vast amounts of data on cellular processes to ...

When people think about health, they often focus on specific organs like the heart or brain. But many changes related to chronic conditions or ageing begin in the smallest units of your body — your ...

Aerobic glycolysis dominates lesion bioenergetics, with lactate promoting histone lactylation, M2 macrophage polarization, CD8⁺ T-cell exhaustion, EMT, and fibrosis that reinforce immune-protected ...

Aging is accompanied by a gradual decline in tissue repair, metabolic flexibility, and immune resilience, ultimately ...