Medical illustration showing how plaque buildup and clot formation can restrict blood flow in arteries. Researchers have developed a luteolin-based nanomedicine that targets and stabilizes these ...
Neratinib, an oral drug commonly used in the treatment of breast cancer, has shown potential in reducing vascular ...
Prior to 1990, many assumed that once cholesterol plaques form in the arteries causing atherosclerosis, it was not reversible. While this is true for plaques that have calcified, what about plaques in ...
To enhance the therapeutic efficacy of ELA-11 and achieve targeted delivery to atherosclerotic plaques, a pH-responsive NP system, mPEG@ELA-11, was developed. This system was engineered to prolong ELA ...
For the longest time, clinicians have treated cardiovascular disease by focusing on diabetes and blood pressure control, reducing cholesterol using medications like aspirin and statins. Despite these ...
Researchers have discovered that the smooth muscle cells that line the arteries of people with atherosclerosis can change into new cell types and develop traits similar to cancer that worsen the ...
This article was reviewed by Craig Primack, MD, FACP, FAAP, FOMA. Atherosclerosis happens when a fatty substance called plaque builds up inside your arteries. There are typically few noticeable ...
Preclinical data suggest neratinib dampens vascular inflammation and atherosclerosis by targeting ASK1 in endothelial cells, ...
Several cardiovascular risk factors, such as advanced age and smoking history, are prevalent among lung cancer patients at the time of the diagnosis and increase their risk of future heart disease, ...