Aminoacyl-tRNA synthetases (aaRSs) are ubiquitous enzymes that provide the critical link between the genetic code and protein biosynthesis. By precisely catalysing the attachment of amino acids to ...
The genetic information stored in DNA is “decoded” to form proteins via the process of translation. This involves the formation of peptide bonds between amino acids bound to transfer RNA (tRNA) ...
Life runs on instructions you never see. Every cell reads DNA, turns that message into RNA, and then builds proteins that ...
Collaborative research by the University of Tokyo and RIKEN Center for Biosystems Dynamics Research has led to the development of a new method for simultaneously synthesizing all transfer RNA (tRNA) ...
tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...
Scientists have found that human ribosomes decode mRNA slower than bacteria, with implications for drug development. Scientists at St. Jude Children's Research Hospital revealed that human ribosomes ...
The process of 'translation' in protein synthesis involves formation of a peptide bond between two amino acids that are attached to two distinct transfer RNAs (tRNAs). For long, scientists have been ...