The Lower East Side Tenement Museum is a museum and National Historic Site located at 97 and 103 Orchard Street in the Lower East Side neighborhood of Manhattan in New York City, United States. The museum's two historical tenement buildings were home to an estimated 15,000 people, from over 20 nations, between 1863 and 2011. The m…The Lower East Side Tenement Museum is a museum and National Historic Site located at 97 and 103 Orchard Street in the Lower East Side neighborhood of Manhattan in New York City, United States. The museum's two historical tenement buildings were home to an estimated 15,000 people, from over 20 nations, between 1863 and 2011. The museum, which includes a visitors' center, promotes tolerance and historical perspective on the immigrant experience.